As part of their ongoing training, students in the virology track participate in a seminar series sponsored by the CVR. This program supports a regular semi-monthly series, with seminars scheduled every other Friday during the academic year, in which leading national researchers are invited to present their work in different areas of virology, gene regulation, cell transformation, and a variety of topics in molecular biology and molecular genetics. These seminars provide a stimulating forum for exchanges of scientific ideas, information and research approaches. In addition, graduate student trainees appointed to the NIH Virology Training grant present their work in an annual symposium that is part of this seminar series, allowing an opportunity for a critical analysis of their data by the CVR faculty.

All seminars are at NOON in Natural Sciences I, Room 1114 unless otherwise noted.


Spring 2020

All spring seminars have been cancelled due to the COVID-19 emergency.

Winter 2020

Jan 10 Dirk Dittmer, PhD
Professor; Department of Microbiology and Immunology, UNC-Chapel Hill; UNC School of Medicine
Exosomes mediate paracrine phenotypes for Kaposi Sarcoma-associated herpesvirus

Jan 31 David Evans, PhD
Professor; Department of Medical Microbiology & Immunology; University of Alberta
Poxvirus recombination and reactivation: Mechanism, applications, and real world implications

Feb 21 Elizabeth Connick, MD
Professor of Medicine, Immunology, and BIO5 Institute; University of Arizona
HIV Exploits B Cell Follicles to Evade Immune Detection: Hiding in Plain Sight!

Fall 2019

Sep 27 Marcus Ernst Peter, PhD
Tom D. Spies Professor of Cancer Metabolism; Professor of Medicine (Hematology and Oncology) and Biochemistry & Molecular Genetics; Northwestern University Feinberg School of Medicine
Killing cancer cells with toxic siRNAs

Oct 11 Suellen Hopfer, PhD, CGC
Department of Population Health & Diseases Prevention; Department of Pediatrics; University of California, Irvine
Contributors to vaccine hesitancy: The case of adolescent HPV vaccination

Nov 15 Paula Cannon, PhD
Distinguished Professor of Molecular Microbiology Immunology; Keck School of Medicine at USC
Genome Editing versus HIV

Spring 2019

Apr 19  Paul Turner, PhD
Elihu Professor of Ecology & Evolutionary Biology; Yale University
Using viruses to select for reduced virulence of bacterial pathogens in human patients 

May 3  Hector Aguilar-Carreno, PhD
Cornell University College of Veterinary Medicine; Department of Microbiology & Immunology
Viral-Host Interactions During Entry and Egress of the Deadly Nipah Virus

May 17  Diane Griffin, MD, PhD
Vice President, U.S National Academy of Sciences; Johns Hopkins Bloomberg School of Public Health, Department of Molecular Microbiology & Immunology
Alphavirus encephalomyelitis: Determinants of outcome

May 17  Elodie Ghedin, PhD
Director, Center for Genomics & Systems Biology; New York University; Departments of Biology, and Global Public Health
Genetic Diversity and Interactions in Flu Infections

Winter 2019

Jan 11  John H. Connor, PhD
Boston University School of Medicine; Department of Microbiology
Evolution and Addiction in Ebola virus replication 

Feb 22  David C. Bloom, PhD
University of Florida College of Medicine; Department of Molecular Genetics & Microbiology
Role of Non-coding RNAs in HSV-1 Latency and Reactivation

Mar 15  Adam Lauring, MD, PhD
University of Michigan Medical School; Department of Medicine, Division of Infectious Diseases
RNA virus mutation rates, another spandrel?

Fall 2018

Oct 5    Yongsheng Shi, PhD
UC Irvine; Department of Microbiology & Molecular Genetics
Host shutoff mechanisms of the Herpes Simplex virus

Nov 2   Melody Li, PhD
UC Los Angeles; Department of Microbiology, Immunology and Molecular Genetics
The role of cellular cofactors and splice variants in the antiviral mechanism of ZAP

Nov 16  Roberto Tinoco, PhD
UC Irvine, School of Medicine; Department of Molecular Biology & Biochemistry
PSGL-1, a new player in the immune checkpoint landscape

Spring 2018

Apr 20    Ted Pierson, PhD
National Institute of Allergy & Infectious Diseases; Laboratory of Viral Diseases, NIH
ZIKV Vaccination and Immunity

May 4    Sumit Chanda, PhD
Sanford-Burnham Institute for Biomedical Research
Systems-based Analyses of Host Pathogen Interactions

May 17   (THU)  Cedric Feschotte, PhD
Special Seminar: co-sponsored w/ MB&B
Cornell University; Department of Molecular Biology & Genetics
Transposable Elements as Catalyst of Convergent Molecular Innovations

May 18   Britt Koskella, PhD
UC Berkeley; Department of Integrative Biology
Examining the Role of Lytic Bacteriophages in the Microbiome

June 1      NIH Virology Training Grant Symposium

William Hu (Sandri-Goldin Lab) – Structure-Function Analysis of the HSV-1 Regulatory Protein ICP27
Margaret Lugin (Kwon Lab) – Hybrid Adeno-associated Viruses for Multi-modal and Versatile Therapy
Steven Wandro (Whiteson Lab) – Coevolution of Enterococcus with lytic phage.
Wendy Ullmer (Semler Lab) – Disruption of Nucleocytoplasmic Trafficking is Required for AUF1 Restriction of Picornavirus Translation in Human Cells 

Winter 2018

Jan 19      Junghae Suh, PhD
Department of Bioengineering, Rice University
Synthetic Virology: Reprogramming Viruses into Controllable Nanodevices

Feb 23    Ann Arvin, MD
Vice Provost and Dean of Research , Department of  Pediatrics and of Microbiology & Immunology, Stanford University
Molecular Mechanisms of Varicella-Zoster Virus Pathogenesis

Feb 28    (WED) Vineet KewalRamani, PhD
Center for Cancer Research, National Cancer Institute, NIH
HIV-1 Nuclear Entry and  Intranuclear Trafficking

Mar 9     Sunnie Thompson, PhD
Department of Microbiology, Center for AIDS Research, Birmingham School of Medicine, University of Alabama
Identification of dengue host factors required for viral translation during a live infection using TUX-MS

Fall 2017

Sept 29      Ilhem Messaoudi Powers, PhD     Department of Molecular Biology & Biochemistry, University of California, Irvine
Mechanisms of protection conferred by recombinant vesicular stomatitis virus–based vaccines against Ebola and Marburg virus infections

Oct 27       Grant McFadden, PhD   Center for Immunotherapy, Vaccines & Virotherapy Biodesign Institute, Arizona State University
The long and winding road from poxvirus tropism to oncolytic virotherapy

Nov 17     Felicia Goodrum, PhD   Department of Immunobiology & BIO5 Institute, University of Arizona
Viral regulation of host trafficking and signaling

Spring 2017

Apr 4       Frederic D. Bushman, PhD
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania
The Human Virome in Health and Disease

Apr 21      Marshall Bloom, MD
Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, National Institute of Health
The enigmatic biology of tick-borne flaviviruses

May 5       Ileana Cristea, PhD
Department of Molecular Biology, Princeton University
Dynamic Proteome Organization and Host Defense during Viral Infection

June 2      NIH Virology Training Grant Symposium

William Hu (Sandri-Goldin Lab) – TBA
Margaret Lugin (Kwon Lab) – TBA
Joshua Smith (Weiss Lab) – TBA
Wendy Ullmer (Semler Lab) – TBA

Winter 2017

Jan 20      John V. Moran, PhD
Department of Human Genetics & Internal Medicine, Investigator, Howard Hughes Medical Institute, University of Michigan Medical School
Studies of a Human Transposable Element

Feb 17      Nicole F. Steinmetz, PhD
Department of Biomedical Engineering, Case Western Reserve University SOM
From black-eyed peas to nanotechnology: plant virus-based nanomedicine

Mar 3       William Paul Duprex, PhD
Department of Microbiology, National Emerging Infectious Diseases Laboratories (NEIDL), Boston University School of Medicine
Modeling the evolutionary trajectories of an expanding Morbillivirus genus: getting in, getting about getting out and about

Fall 2016

Nov 18      David T. Pride, MD, PhD     Department of Pathology & Medicine, Associate Director, Microbiology, University of California, San Diego
Role and spread of viruses in the human microbiome

Oct 14       Andrew Noymer, PhD     Department of Public Health, University of California, Irvine
Optimal measles vaccination schedules in developing countries: Insights from mathematical modeling

Sept 30     Jennifer B.H. Martiny, PhD     Department of Ecology & Evolutionary Biology, University of California, Irvine
The evolutionary ecology of marine bacteriophage

Spring 2016

May 27      NIH Virology Training Grant Symposium

William Hu (Sandri-Goldin Lab) – Structure-Function Analysis of the HSV-1 Regulatory Protein ICP27
Kurt Patterson (Sandmeyer Lab) – Ty3 Retrotransposition: Preferential Targeting at RNA Pol III Transcribed Genes
Joshua Smith (Weiss Lab) – Directed Evolution of a Soluble Human Caveolin-1 Variant
Dylan Flather (Semler Lab) – Defining the functional role of nuclear proteins in rhinovirus replication

May 13      Heinz Feldmann, MD, PhD    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, NIH
Emerging Viruses – From Disease Modeling to Vaccines

Apr 15      CANCELLED – Haig H. Kazazian, Jr., MD     Department of Pediatrics, Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine
A potential role for somatic retrotransposition in cancer

Apr 1       Matthew J. Evans, PhD    Department of Microbiology, Icahn School of Medicine at Mount Sinai
Plasticity of tropism defining hepatitus C virus host interactions

Winter 2016

Feb 26      Alan N. Engelman, PhD     Department of Medicine, Harvard Medical School
Integrase Structure and Inhibition of HIV-1 Replication

Feb 12      Christopher S. Sullivan, PhD     Dept of Molecular Genetics & Microbiology, The University of Texas at Austin
RNAi, whose side are you on? Exploring gene silencing during virus infection of mammalian cells

Jan 15      Maribeth V. Eiden, PhD     Laboratory of Cellular and Molecular Regulation, National Institute of Mental Health, NIH
Koala Retroviruses: Evolution and Disease Dynamics
LOCATION CHANGE – Tamkin Student Lecture Building, F114

Fall 2015

Dec 11      Michael J. Buchmeier, PhD     Division of Infectious Diseases, Dept of Medicine, Dept of Molecular Biology & Biochemistry, University of California, Irvine
 The Exciting New World of Arenaviruses 
LOCATION CHANGE – Tamkin Student Lecture Building,  F114

Nov 13     Clodagh O’Shea, PhD     Molecular & Cell Biology Lab, Salk Institute for Biological Studies
Exploiting viruses to understand and treat cancer 

Oct 16      Dominik Wodarz, PhD     Department of Ecology & Evolutionary Biology, University of California, Irvine
Virus dynamics: insights from mathematical models

Spring 2015

May 29      NIH Virology Training Grant Symposium

Kurt Patterson (Sandmeyer Lab) – Ty3 retrotransposition: Preferential targeting at RNA pol III transcribed genes
Mitchell Schacht (Sandri-Goldin Lab) – Structure-function analysis of HSV-1 ICP27
Joshua Smith (Weiss Lab) – Investigating the interaction between human caveolin-1 and HIV gp41 using a soluble caveolin variant
Dylan Flather (Semler Lab) – Defining and characterizing the functional role of nuclear proteins in enterovirus replication

May 15      Alan D. Frankel, PhD Department of Biochemistry & Biophysics, University of California, San Francisco
Architecture and evolution of the HIV RNA export complex

May 01      Ralph S. Baric, PhD Department of Epidemiology, University of North Carolina at Chapel Hill
Dengue virus structure-guided immunogen design

Apr 17      Harmit S. Malik, PhD Basic Sciences and HHMI Investigator, Fred Hutchinson Cancer Research Center, Seattle
Rules of engagement: molecular arms-races between host and viral genomes

Apr 03      Sandra K. Weller, PhD Department of Molecular Biology & Biophysics, University of Connecticut Health Center
Herpes simplex virus overcomes antiviral elements of the cellular DNA damage response to replicate its genome

Winter 2015

Feb 27      Erica Ollmann Saphire, PhD Department of Immunology & Microbial Science, Scripps Research Institute, La Jolla
Antibodies against Ebola virus: The road map

Feb 20      (3PM) Jacques Izopet, MD, PhD Laboratoire de Virologie, Institut Fédératif de Biologie, Toulouse, France
Hepatitis E virus infection: From pathogenesis to treatment

Feb 18      (WED) W. Ian Lipkin, MD Center for Infection and Immunity, Mailman School of Public Health, Columbia University
Small game hunting

Feb 13      Felicia D. Goodrum, PhD Department of Immunobiology, University of Arizona, Tucson
Virus-host interactions controlling HCMV persistence

Jan 16      Alejandro Reyes Muñoz, PhD Department of Biological Sciences, Universidad de los Andes, Bogotá, Colombia
Characterizing the human gut virome: New challenges, new tools

Fall 2014

Dec 12       Ilhem Messaoudi, PhD Department of Biomedical Sciences, University of California, Riverside
Defining host-pathogen interactions during VZV infection using a nonhuman primate model

Nov 17       Ronald Swanstrom, PhD Departments of Biochemistry & Biophysics; Microbiology & Immunology, University of North Carolina at Chapel Hill
HIV transmission, evolution, and pathogenesis: From single genomes to deep sequencing

Oct 31       Ren Sun, PhD Department of Molecular & Medical Pharmacology, University of California, Los Angeles
Quantitative viral genetics at single nucleotide resolution

Oct 17       Luis P. Villarreal, PhD Department of Molecular Biology & Biochemistry, University of California, Irvine
RNA consortia: The boss of virus and life

Sept 16       Douglas J. Mahoney, PhD Department of Microbiology, Immunology and Infectious Diseases; University of Calgary
Oncolytic rhabdoviruses for treating cancer

Spring 2014

Jun 13       Douglas Jolly, PhD Executive Vice President, Research & Pharmaceutical Development, Tocagen Inc, San Diego
Toca 511 – A retroviral replicating vector encoding a prodrug activating gene and a potential therapeutic for recurrent primary brain cancer in clinical trials

Jun 06       Suzanne Sandmeyer, PhD Department of Biological Chemistry; Director, Genomics High-Throughput Facility, University of California, Irvine
Parsing the non-randomness of retroelement integration

May 23       Terence S. Dermody, MD Departments of Pediatrics and Pathology, Microbiology & Immunology, Vanderbilt University School of Medicine
Reovirus invasion of the brain: A tale of two receptors

May 09       Timothy Tellinghuisen, PhD Department of Infectious Diseases, The Scripps Research Institute, Florida Campus
The hepatitis C virus NS5A protein regulates RNA replication and assembly

Apr 25       Sonja M. Best, PhD Chief, Innate Immunity and Pathogenesis Unit, Rocky Mountain Laboratories
New insight into the control of type I interferon signaling revealed by flavivirus mechanisms of antagonism

Apr 11       Mark Young, PhD Departments of Plant Sciences & Plant Pathology; Microbiology, Montana State University – Bozeman
Advances in archaeal virus structures and functions

Winter 2014

Jan 10     Olve Peersen, PhD     Department of Biochemistry & Molecular Biology, Colorado State University
Structure and fidelity engineering of picornaviral polymerase elongation complexes

Jan 24     Carolyn Coyne, PhD     Department of Microbiology & Molecular Genetics, University of Pittsburgh
High-throughput RNAi screening identifies novel regulators of the secretory pathway and viral infections

Feb 21     SEMINAR CANCELLED     Douglas J. Jolly, PhD     Executive VP, Research & Pharmaceutical Development, Tocagen, Inc.
Toca 511 – A retroviral replicating vector encoding a prodrug activating gene and a potential therapeutic for recurrent primary brain cancer in clinical trials

Mar 14     Michaela U. Gack, PhD     Department of Microbiology & Immunobiology, Harvard Medical School      LOCATION CHANGE – Natural Sciences I, Room 1114
Phosphatase-induced antiviral signaling and viral immune escape

Fall 2013

Oct 11     Junghae Suh, PhD     Department of Bioengineering, Rice University
Reprogramming viruses for biomedicine

Oct 25     Colin Parrish, PhD     Department of Microbiology & Immunology, Cornell University
Understanding the emergence of epidemic viruses in new hosts- the cases of canine parvovirus and canine influenza virus

Nov 08     Irene Munk Pedersen, PhD     Department of Molecular Biology & Biochemistry, University of California, Irvine
miR-regulation of jumping DNA originated from yesterday’s viruses

Spring 2013

Apr 12     Blossom A. Damania, PhD     Department of Microbiology & Immunology, University of North Carolina – Chapel Hill
KSHV: Latency and reactivation

Apr 26     Susan R. Ross, PhD     Department of Microbiology, University of Pennsylvania
Identification of cellular genes involved in New World arenavirus entry
SPECIAL LOCATIONNelson Auditorium, Irvine Hall

May 10     Paula M. Cannon, PhD     Departments of Molecular Microbiology & Immunology; Biochemistry & Molecular Biology; Pediatrics, University of Southern California
Using stem cells to engineer an HIV-resistant immune system

May 24     Andrew Pekosz, PhD     Departments of Molecular Microbiology & Immunology; Environmental Health Sciences, Johns Hopkins University
Influenza A virus infection and particle assembly in respiratory epithelial cells

Jun 07     NIH Virology Training Grant Symposium

Dylan Flather (Semler Lab) – Isolation of RNP complexes associated with poliovirus RNA during replication
Brett Marro (Lane Lab) – A protective role for the chemokine receptor CXCR2 on oligodendrocytes during MHV-induced neuroinflammation
Megan Angelini (Buchmeier Lab) – SARS-Coronavirus nonstructural proteins 3, 4, and 6 induce double membrane vesicles

Jun 11     Ganes C. Sen, PhD     Department of Molecular Genetics, Cleveland Clinic
Innate immune responses to virus infection

Winter 2013

Jan 11     Joseph L. DeRisi, PhD     Department of Biochemistry & Biophysics, University of California, San Francisco
Strange tails:  Genomics and infectious disease

Jan 25     Charles L. Brooks III, PhD     Department of Chemistry & Biophysics, University of Michigan
Multi-scale explorations of virus maturation dynamics and mechanics

Feb 22     Sujan Shresta, PhD     Center for Infectious Disease, La Jolla Institute for Allergy & Immunology
Protective vs. pathogenic effects of dengue vaccination

Mar 15     Karen L. Beemon, PhD     Department of Biology, Johns Hopkins University
Retroviral oncogenesis:  Role of TERT and microRNAs

Fall 2012

Oct 12     Charles L. Brooks III, PhD     Department of Chemistry & Biophysics, University of Michigan
Multi-scale explorations of virus maturation dynamics and mechanics

Oct 26     Jerome A. Zack, PhD     Department of Microbiology, Immunology & Molecular Genetics; Director UCLA Center for AIDS Research, University of California, Los Angeles
A stem cell approach to engineering T cell immunity towards cancer and HIV

Nov 09     Anthony A. James, PhD     Department of Microbiology & Molecular Genetics; Department of Molecular Biology & Biochemistry, University of California, Irvine
Genetic engineering of mosquitoes to block dengue virus transmission

Nov 30     Takayuki Nitta, PhD     Department of Molecular Biology & Biochemistry, University of California, Irvine
Murine leukemia virus glyco-gag facilitates retrovirus replication

Spring 2012

Apr 06     Eric Delwart, PhD     Department of Laboratory Medicine, University of California, San Francisco
Viral discovery:  Sipping from the metagenomics fire hose

Apr 20     Thomas E. Lane, PhD     Department of Molecular Biology & Biochemistry Director, Multiple Sclerosis Research Center, University of California, Irvine
Neural progenitor cells and repair in a viral model of demyelination

May 04     Eva Harris, PhD     Division of Infectious Diseases and Vaccinology, University of California, Berkeley
Natural and therapeutic antibodies and the B cell response against dengue virus

May 18     K. Eric Wommack, PhD     Plant & Soil Sciences; Biological Sciences, University of Delaware
The virosphere:  Ecological, biological and genetic contrasts of viruses across the biosphere

Winter 2012

Jan 13     Kurt Gustin, PhD     University of Arizona College of Medicine, Phoenix, Department of Basic Medical Sciences
Impact of picornavirus infection on trafficking of cellular protein and mRNA

Feb 10     Thomas Hope, PhD     Northwestern University Medical School, Department of Cell & Molecular Biology
Using a better understanding of the mechanisms of HIV sexual transmission to develop vaccines and microbicides

Feb 24     Kathleen Boris-Lawrie, PhD     Ohio State University, Dept of Veterinary Biosciences
Thriving under stress: Selective translation of HIV-1 during virus-mediated impairment of eIF4E translation activity

Mar 16     Barbara Sherry, PhD     North Carolina State University, Dept of Molecular Biomedical Sciences
Uncovering the cardiac response to viral infection:  Directed and discovery approaches

Fall 2011

Sept 23     Young Jik Kwon, PhD     UC Irvine, Dept of Pharmaceutical Sciences
Synthetically-reinforced viruses for effective, tunable & synergistic gene therapy

Oct 14     Robin M. Bush, PhD     UC Irvine, Dept of Ecology & Evolutionary Biology
Incorporating evolutionary analysis into influenza vaccine and drug design

Oct 28     Kevin B. Walsh, PhD   Postdoctoral Fellow, The Scripps Research Institute
Control of respiratory virus infection:  Role of cytokine storm, sphingosine-1- phosphate 1 receptor   

Spring 2011

Apr 08     Marilyn Roossinck, PhD     The Samuel Roberts Noble Fnd, Plant Biol DivVirus ecology:
They aren’t the bad guys anymore

May 06     Forest Rohwer, PhD     San Diego State University, Cell & Mol Biology
Ecology of the human virome

May 20     NIH Virology Training Grant Symposium

Megan Angelini (Buchmeier Lab) – Understanding the role of SARS-Coronavirus nsp3, nsp4 and nsp6 in double membrane vesicle assembly
Agnes Hajduczki (Weiss Lab) – Engineering soluble membrane proteins by phage display
Erinn Parnell (Bernard Lab) – Defining the role of cholinergic signaling in Human Papilloma Virus cervical carcinogenesis

Jun 03     Don Gilden, MD     Univ of CO School of Medicine, Dept of Neurology
The neurobiology of Varicella Zoster Virus infection

Winter 2011

Jan 14     Charles Rice, PhD     The Rockefeller University, Lab of Virology & ID
Antiviral activities of type I interferon-stimulated genes

Feb 11     James Alwine, PhD     University of Pennsylvania, Dept of Cancer Biology
Taking advantage of cellular stress response: how human CMV deals w/ stress

Mar 03    Julie Pfeiffer, PhD     University of Texas, Southwestern Medical Center
Complex interactions in the gut:  enteric viruses, bacteria, mucosa & immunity

Fall 2010

Other Related Seminars and Symposia:
The UCI Bio Sci Events Calendar